| Rank | Abbreviation | Meaning |
|---|
| ***** | UPCO | Utila Power Company (Utila, Honduras)
| |
| ***** | UPCO | Universal Propulsion Company, Inc.
| |
| **** | UPCO | Under Pressure Cut Off (valve)
| |
| *** | UPCO | Universal Potash Corp Inc. (OTC Bulletin Board [OTCBB])
| |
| *** | UPCO | Unidad de Planificación y Coordinación Operativa
| |
| *** | UPCO | Universidad Pontificia de Comillas (Catholic university; Madrid, Spain)
| |
| * | UPCO | Unilateral Posterior Semicircular Canal Occlusion (biomedical sciences)
| |
| * | UPCO | University of the Philippines Cornell
| |
| * | UPCO | University Place Community Organization
| |
| * | UPCO | United Pharmacal Co.
| |
| * | UPCO | Uptown Plain City Organization
| |